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Stent

History

June 2020
CE Certificate for MSMĀ® DEPERI - peripheral Drug Eluting Balloon

July 2019
Market introduction of MSMĀ® CARDIO - Wireless Pocket Ultrasound System

2019
EC Certificate for a new coronary product

2017
EC Certificates of new peripheral products

2016
EC Certificates of new coronary products

2015
Development of new coronary products

2014
Development of new peripheral products

December 2010
EC Certification for Galaxy PTCA dilatation catheter,
Galaxy HP High Pressure PTCA Balloon Catheter,
Uni-Pass Hemostasis valve,
Marathon coronary stent system,
Comet coronary stent system
Certificate Number: 974 B CE for use the CE 0473 marking.

August 2010
EC Certification for Nova, SuperNova, Stream
Certificate Number: 974 CE for use the CE 0473 marking.

July 2010
introduction of quality management system according to DIN EN ISO 13485:2010

January 2010
R/D of Aspiration catheter "Stream"

November 2009
R/D of PTA balloon catheter "SuperNova 0.014" for "Below the Knee" indication

December 2008
R/D of PTA balloon catheter "Nova 0.035"

July 2007
introduction of quality management system according to DIN EN ISO 13485:2003

October 2006
R/D of plasma - implanted nano-technologie surfaces for heart implants - e.g. Plug, Occluder, ...

September 2005
R/D of nano-technology surfaces for medical implants - e.g. Vena Cava Filter

December 2004
MSM® presents a new DES (Drug Eluting Stent) Generation with "Intima-like" Coating Technology: Known proven Paclitaxel w/w approved drug with a dose of 1 µg/mm² ± 5%.
Release of about 10% during Early Burst Rate within the first 2 days; Release of about 30% during Therapeutic Period within 4 weeks; about 40% release after 6 month.

November 2004
market introduction of MSM® LASER COBALT CHROMIUM - Stent with surface nano-technology. MSM® Coronary Stent has rounded thin struts for easy access - down to .0028" strut thickness.Best clinical outcomes by extraordinary high bio-compatibility! ( ISAR STEREO II-trial: Schühlen, H. et al.; presented at TCT 2002; "Less restenosis because of thinner struts").

October 2004
market introduction of MSM® - LASER TANTALUM CHROMIUM - Stent with surface nano-technology! This MSM® Coronary Stent is made like a tantalum chromium superalloy on "sandwich"- technology that allows us to reduce strut thickness without compromising radio-opacity and radial strength. Best clinical outcomes by extraordinary high biological compatibility! Just .0024" thick ! ( ISAR STEREO II-trial: Schühlen, H. et al.; presented at TCT 2002; "Less restenosis because of thinner struts").

September 2004
R/D of a new Stent Delivery System CIS (Coronary Implant System): Atraumatic rounded micro soft tip at the top of a tapered minimized lesion entry profile .017". Tailor-made balloon shoulders with 30° cone angles. Optimized balloon length with max. 0.5 mm overhang. Minimum system profile .376". Hydrophilic coated - Semi compliant. Optimized transition zone with tapered hypotube for kink protection and continuous stiffness decrease from proximal to distal shaft.

August 2004
MSM® is recognized as leader in stent innovation and multiple stent coatings with surface nano-technology.

March 2003
market-introduction of a "POL-surface" (ProtectiveOxideLayer)

January 2003
market-introduction of "bio-ceram" product line

Dezember 2002
US-patent issue, STENT FOR TRANSLUMINAL IMPLANTATION, Patent No. US 6.497.723

September 2002
Appl. No. 09/486.794 for MSM-Stent; result of long term trial with high-risk patients show outstanding low re-stenosis of 15%

June 2002
value line - euco-Stent and euco-CIS-System

March 2002
market-introduction of MSM dental product line

December 2001
MSM AG is manufacturing approx. 75 different products

October 2001
market-introduction of BMS-Stent length 21 mm

March 2001
market-introduction of stent lengths 6 mm and 12 mm as small vessel (vs) BMS-Stents, also to apply as Primary-CIS-System

February 2000
market-introduction of a value stent product line "HT"

December 1999
MSM AG is manufacturing approx. 50 different products

June 1999
market-introduction of a small vessel (sv) version, to be used for primary-stenting-procedures (Direct Stenting) - too

May 1999
introduction of quality management system according to
ISO 9001 and EN 46001

December 1998
MSM AG is manufacturing approx. 35 different products, like coronary-Bare-Stents, CIS-Systems and PTCA-Catheters

October 1998
begin of research regarding Bioresorbable Vascular Stents

June 1998
introduction of quality management system according to
ISO 9002 and EN 46002

April 1998
market-introduction of a Coronar Implant System (CIS), a PTCA-Catheter with a premounted MSM-Stent (BMS or HV)

March 1998
market-introduction of PTCA-Catheter

October 1997
market-introduction of high vaccum treated "Bare"-Stents (HV)

September 1997
begin of long term trial (5 years) with high-risk patients, University Hospital of Ulm - cardiological department

August 1997
market-introduction of "Bare"-Stents with a Bio-Metal-Surface "BMS" after receiving CE-approval

April 1997
foundation of "Micro Science Medical AG" (MSM AG), a developing and manufacturing company

August 1996
beginning of coronary Stent development by Euco Medical GmbH and engineering-office Bernd Starck